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Manuela Velázquez Prieto
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Jaime E. Poquet Jornet
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Volume 19 - Issue 3, May-June 2017
ORIGINAL
ASSESSMENT OF EFFECTIVENESS OF PREVENTION OF MOTHER TO CHILD TRANSMISSION OF HUMAN IMMUNODEFICIENCY VIRUS IN ASELLA HOSPITAL, ETHIOPIA
ABDULA MAMA, ZELEKE TILAHUN, SHIBESHI WORKINEH


Objective: This study was aimed to assess effectiveness of PMTCT programs through determination of the outcome of HIV exposed infants at Asella teaching and referral hospital from February 2012-2015.

Method: A retrospective cross sectional study was conducted. Mothers-infant pairs HIV status was obtained from medical records using structured questionnaires and entered into EPI info version 3.5.1 and analyzed by statistical package for social science version 21. Bivariate and Multivariate logistic regression analysis was employed to see the effect of each independent variable on the outcome variable.

Results: The results indicated that 126 (93.1%) mothers and 98 (75.3%) infants received antiretroviral (ARV) prophylaxes, however, 32 (24.6%) infants were not receiving ARV prophylaxes. 105 (80.8%) infants were tested after six weeks using deoxyribonucleic acid-polymerase chain reaction (DNA/PCR). Infant HIV infection rate was 3.1%, 3.8%, and 7.7% at six weeks, six months and overall 18 months respectively. Mothers illness during pregnancy [Adjusted odds ratio (AOR) = 20.4], mothers failure to receive antiretroviral therapy during
pregnancy/breast feeding (AOR = 17.2), home delivery (AOR = 8), infant birth weight (AOR = 2.7) and mixed infant feeding (AOR = 2) were the factors that affecting HIV free survival in this study.

Conclusion: This study showed that 92.3% of the infants were having HIV free survival at 18 months. However, infant HIV infection rate of 7.7% is above that required for elimination of mother to child transmission (eMTCT) of HIV. The PMTCT intervention uptake with specific reference to ARV usage for PMTCT shows higher uptake in mothers than in infants. However, the uptake of ARV in infants falls below targets required for eMTCT of HIV, and the targets set in the Ethiopian national strategic plan for eMTCT of HIV <5% by 2015.

EFFECTIVENESS – HIV EXPOSED INFANTS – MTCT – PMTCT



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